Endocrine Abstracts

Riedel thyroiditis, an uncommon form of chronic thyroiditis in which the thyroid gland is replaced by fibrous tissue, is difficult to differentiate from the fibrous variant of Hashimoto thyroiditis or lymphoma. We report a patient illustrating this. A 54 year old lady with a long standing goitre and 3 year history of stable hypothyroidism was referred for progressive thyroid gland enlargement over several months, dysphagia and an increasing thyroxine requirement. Clinically, s...

In a retrospective cohort study, we reviewed the medical notes of patients with severe hyponatreaemia admitted to acute medical unit at Blackpool Hospital between January and March 2012. We assessed the severity, causes of hyponatraemia, length of stay and mortality in patients with hyponatraemia.We identified 25 patients with plasma sodium ≤120 mmol/l, 5 of whom were admitted twice during the study period. Their average age was 70 (range 30–9...

Hypomagnesaemia usually occurs secondary to decreased intestinal absorption or excessive renal excretion. There have been a few reports recently suggesting an association between PPIs and hypomagnesaemia.A 65-year-old lady was referred to the endocrine clinic for investigation of hypomagnesaemia found on routine testing. Serum magnesium was 0.27 mmol/l (normal 0.7–1.0), with corrected serum calcium of 2.0 mmol/l (2.12–2.63), and normal PTH and ...

Introduction: To assess outcome for patients with acromegaly treated at Royal Preston Hospital since 1st of January 2000.Results: Out of 22 patients (12 presenting in the last 2 years) 20 had endoscopic transsphenoidal hypophysectomy and two were managed medically. Headaches, visual disturbance and characteristic morphological features were the main presenting problems. 4 were microadenomas and 18 macroadenomas\. Exact dimensions were only available in 1...

31 years old female presented to casualty with acute abdominal pain and vomiting. The physical findings showed acutely unwell female with persistent regular tachycardia and a large goitre with a bruit. There were no demonstrable eye signs indicating Grave’s disease. Initial investigation showed profound high anion gap metabolic acidosis (PH-7.13,HCO3-5.1, CL-113.6 BE-22.1PCO2 2.69,PO2-12.5) and severe hyperthyroidism (FT4-44 picomol per litre,FT3-24.8 picomol per litre,TS...

Transphenoidal surgery is an effective treatment option in patients with pituitary tumours associated with compression of the optic chiasm or hormone hypersecretion. Surgery carries with it a risk of the development of new pituitary hormone deficits but also the potential for recovery of existing pituitary hormone deficits. We have examined data concerning pituitary function in 80 patients who underwent endoscopic transphenoidal pituitary surgery at Royal Preston Hospital....